CACNB2 antibody (Middle Region)

Catalog No. ABIN2776361

This Rabbit Polyclonal antibody specifically detects CACNB2 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse, Dog, Pig and Zebrafish (Danio rerio).

Quick Overview for CACNB2 antibody (Middle Region) (ABIN2776361)

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse, Dog, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CACNB2 Antibody

Binding Specificity: Middle Region

Sequence: DACEHLADYL EAYWKATHPP SSSLPNPLLS RTLATSSLPL SPTLASNSQG

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against CACNB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CACNB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 608 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACNB2

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Alternative Name: CACNB2

Background: CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Alias Symbols: CACNLB2, FLJ23743, MYSB, CAVB2
Protein Interaction Partner: REM1, PRKACA,
Protein Size: 608

Molecular Weight: 68 kDa

Gene ID: 783

NCBI Accession: NM_201572, NP_963866

UniProt: A6PVM7

Pathways: Skeletal Muscle Fiber Development