MED21 antibody (C-Term)

Catalog No. ABIN2776417

This Rabbit Polyclonal antibody specifically detects MED21 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig and Pig.

Quick Overview for MED21 antibody (C-Term) (ABIN2776417)

Target: MED21 (Mediator Complex Subunit 21 (MED21))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED21 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MED21 Antibody

Binding Specificity: C-Term

Sequence: EENHEAATCL EDVVYRGDML LEKIQSALAD IAQSQLKTRS GTHSQSLPDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MED21. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 144 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MED21

Target: MED21 (Mediator Complex Subunit 21 (MED21))

Alternative Name: MED21

Background: The Mediator is a multiprotein coactivator that is required by DNA-binding transcription factors for transcriptional activation of polymerase II-transcribed genes. MED21 is a Mediator subunit predicted to reside in the middle module and appears to be a core subunit found in nearly all Mediator preparations.
Alias Symbols: SRB7, SURB7
Protein Interaction Partner: MAGEB4, SSC5D, ZNF655, BLOC1S6, MED21, CDK8, MED19, MED26, UBC, HTT, FBXW7, MED11, MED8, MED28, MED29, MED18, MED4, MED16, MED6, MED13, MED12, MED24, MED17, MED14, MED22, MED1, ELAVL1, VAV2, SKP1, THRA, THRB, MED10, TP53, SREBF1, ZC3H13, ZSCAN1, PCBD2, TA
Protein Size: 144

Molecular Weight: 15 kDa

Gene ID: 9412

NCBI Accession: NM_004264, NP_004255

UniProt: Q13503

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha