VSX1 antibody (Middle Region)

Catalog No. ABIN2776514

Product Details anti-VSX1 Antibody

Target: VSX1 (Visual System Homeobox 1 (VSX1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Cow, Dog, Pig, Saccharomyces cerevisiae, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VSX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FLPPRGPEPA APLAPSRPPP ALGRQKRSDS VSTSDEDSQS EDRNDLKASP

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 86%, Yeast: 86%

Characteristics: This is a rabbit polyclonal antibody against VSX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human VSX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 365 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VSX1

Target: VSX1 (Visual System Homeobox 1 (VSX1))

Alternative Name: VSX1 (VSX1 Products)

Synonyms: VSX1 antibody, CAASDS antibody, KTCN antibody, KTCN1 antibody, PPCD antibody, PPD antibody, RINX antibody, CHX10-1 antibody, CHX10-like antibody, visual system homeobox 1 antibody, visual system homeobox 1 L homeolog antibody, visual system homeobox 1 homolog, chx10-like antibody, Vsx1 antibody, VSX1 antibody, Tsp_01485 antibody, vsx1.L antibody, vsx1 antibody

Background: VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. Two transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: KTCN, PPCD, PPD, RINX, KTCN1, CAASDS
Protein Size: 365

Molecular Weight: 38 kDa

Gene ID: 30813

NCBI Accession: NM_014588, NP_055403

UniProt: Q9NZR4