MLXIP antibody (Middle Region)

Catalog No. ABIN2776519

There is 1 publication for this product available. The Rabbit Polyclonal anti-MLXIP antibody is suitable to detect MLXIP in samples from Human, Mouse, Dog and Rabbit. It has been validated for WB and IHC.

Quick Overview for MLXIP antibody (Middle Region) (ABIN2776519)

Target: MLXIP (MLX Interacting Protein (MLXIP))

Reactivity: Human, Mouse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLXIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MLXIP Antibody

Binding Specificity: Middle Region

Purpose: MLXIP Antibody - middle region

Sequence: DEQGCEHTSR TEDPFIQPTD FGPSEPPLSV PQPFLPVFTM PLLSPSPAPP

Predicted Reactivity: Dog: 100%, Human: 100%, Mouse: 79%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against MLXIP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MLXIP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35891-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-MLXIP antibody (ABIN2776519)

Stoltzman, Peterson, Breen, Muoio, Billin, Ayer: "Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6912-7, (2008) (PubMed).

Target Details for MLXIP

Target: MLXIP (MLX Interacting Protein (MLXIP))

Alternative Name: MLXIP

Background:

Background Information: MONDOA forms heterodimers with MLX (MIM 602976) that can bind to and activate transcription from CACGTG E boxes.

Gene Name: MLX interacting protein

Alternative Symbols: MIR, MONDOA, bHLHe36

Protein Name: MLX-interacting protein

Molecular Weight: 101kDa

Gene ID: 22877

NCBI Accession: NP_055753

UniProt: Q9HAP2