SLIRP antibody (N-Term)

Catalog No. ABIN2776583

This Rabbit Polyclonal antibody specifically detects SLIRP in WB and IHC. It exhibits reactivity toward Human, Cow, Dog, Horse, Pig, Rabbit and Sheep.

Quick Overview for SLIRP antibody (N-Term) (ABIN2776583)

Target: SLIRP (SRA Stem-Loop Interacting RNA Binding Protein (SLIRP))

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLIRP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SLIRP Antibody

Binding Specificity: N-Term

Purpose: C14ORF156 Antibody - N-terminal region

Sequence: PFDKETGFHR GLGWVQFSSE EGLRNALQQE NHIIDGVKVQ VHTRRPKLPQ

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 86%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against C14ORF156. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C14ORF156

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112773

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLIRP

Target: SLIRP (SRA Stem-Loop Interacting RNA Binding Protein (SLIRP))

Alternative Name: C14ORF156

Background:

Background Information: As a RNA-binding protein, C14orf156 acts as a nuclear receptor corepressor. It probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. C14orf156 binds the STR7 loop of SRA RNA. It is also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.

Gene Name: SRA stem-loop interacting RNA binding protein

Alternative Symbols: DC50, PD04872, C14orf156

Protein Name: SRA stem-loop-interacting RNA-binding protein, mitochondrial

Molecular Weight: 12kDa

Gene ID: 81892

NCBI Accession: NP_112487

UniProt: Q9GZT3