SRSF12 antibody (Middle Region)

Catalog No. ABIN2776616

Cited in 1 publication. The Rabbit Polyclonal anti-SRSF12 antibody (ABIN2776616) specifically detects SRSF12 in WB. The antibody is reactive with Human, Mouse, Cow, Guinea Pig, Horse, Rabbit, Dog and Rat samples.

Quick Overview for SRSF12 antibody (Middle Region) (ABIN2776616)

Target: SRSF12 (serine/arginine-Rich Splicing Factor 12 (SRSF12))

Reactivity: Human, Mouse, Cow, Guinea Pig, Horse, Rabbit, Dog, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SRSF12 Antibody

Binding Specificity: Middle Region

Purpose: SRrp35 Antibody - middle region

Sequence: RSRSKSLQKR SKSIGKSQSS SPQKQTSSGT KSRSHGRHSD SIARSPCKSP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SRrp35. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRrp35

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41089-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SRSF12 antibody (ABIN2776616)

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Target Details for SRSF12

Target: SRSF12 (serine/arginine-Rich Splicing Factor 12 (SRSF12))

Alternative Name: SRrp35

Background:

Background Information: SRrp35 is a splicing factor that seems to antagonize SR proteins in pre-mRNA splicing regulation.

Gene Name: Serine/arginine-rich splicing factor 12

Alternative Symbols: SFRS19, SRrp35, SFRS13B

Protein Name: Serine/arginine-rich splicing factor 12

Molecular Weight: 30kDa

Gene ID: 135295

NCBI Accession: NP_542781

UniProt: Q8WXF0

Pathways: Ribonucleoprotein Complex Subunit Organization