HEXIM2 antibody (N-Term)

Catalog No. ABIN2776632

This Rabbit Polyclonal antibody specifically detects HEXIM2 in WB. It exhibits reactivity toward Human, Rat, Pig, Dog and Horse.

Quick Overview for HEXIM2 antibody (N-Term) (ABIN2776632)

Target: HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))

Reactivity: Human, Rat, Pig, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEXIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HEXIM2 Antibody

Binding Specificity: N-Term

Purpose: HEXIM2 Antibody - N-terminal region

Sequence: MATPNQTACN AESPVALEEA KTSGAPGSPQ TPPERHDSGG SLPLTPRMES

Predicted Reactivity: Dog: 93%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HEXIM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HEXIM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41121-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HEXIM2

Target: HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))

Alternative Name: HEXIM2

Background:

Background Information: HEXIM2 belongs to the HEXIM family. It is transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor.In cooperation with 7SK snRNA, HEXIM2 sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

Gene Name: Hexamethylene bis-acetamide inducible 2

Alternative Symbols: L3

Protein Name: Protein HEXIM2

Molecular Weight: 31kDa

Gene ID: 124790

NCBI Accession: NP_653209

UniProt: Q96MH2