DCP2 antibody (Middle Region)

Catalog No. ABIN2776651

The Rabbit Polyclonal anti-DCP2 antibody (ABIN2776651) specifically detects DCP2 in WB. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Dog, Horse, Pig, Cow and Rabbit samples.

Quick Overview for DCP2 antibody (Middle Region) (ABIN2776651)

Target: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Horse, Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DCP2 Antibody

Binding Specificity: Middle Region

Purpose: DCP2 Antibody - middle region

Sequence: KQYQDSPNQK KRTNGLQPAK QQNSLMKCEK KLHPRKLQDN FETDAVYDLP

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DCP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DCP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41149-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DCP2

Target: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Alternative Name: DCP2

Background:

Background Information: DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-539 AY135173.1 1-539 540-1992 AK090564.1 481-1933 1993-8947 AC008536.7 154323-161277

Gene Name: DCP2 decapping enzyme homolog (S. cerevisiae)

Alternative Symbols: NUDT20

Protein Name: m7GpppN-mRNA hydrolase

Molecular Weight: 48kDa

Gene ID: 167227

NCBI Accession: NP_689837

UniProt: Q8IU60