RHOU antibody (N-Term)

Catalog No. ABIN2776720

This Rabbit Polyclonal antibody specifically detects RHOU in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig and Zebrafish (Danio rerio).

Quick Overview for RHOU antibody (N-Term) (ABIN2776720)

Target: RHOU (Ras Homolog Gene Family, Member U (RHOU))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RHOU Antibody

Binding Specificity: N-Term

Purpose: Rhou Antibody - N-terminal region

Sequence: GRGRAGGAEG RGVKCVLVGD GAVGKTSLVV SYTTNGYPTE YIPTAFDNFS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 79%, Rabbit: 100%, Rat: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Rhou. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41273-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHOU

Target: RHOU (Ras Homolog Gene Family, Member U (RHOU))

Alternative Name: Rhou

Background:

Background Information: Rhou acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Rhou stimulates quiescent cells to reenter the cell cycle. Rhou has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.

Gene Name: Ras homolog gene family, member U

Alternative Symbols: Ar, Arhu, G28K, WRCH, WRCH-, WRCH1, mG28K, CDC42L, WRCH-1, CDC42L1, AI182090, 2310026M05Rik

Protein Name: Rho-related GTP-binding protein RhoU

Molecular Weight: 28kDa

Gene ID: 69581

NCBI Accession: NP_598716

UniProt: Q9EQT3