RHOU antibody (C-Term)

Catalog No. ABIN2776721

This Rabbit Polyclonal antibody specifically detects RHOU in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig and Guinea Pig.

Quick Overview for RHOU antibody (C-Term) (ABIN2776721)

Target: RHOU (Ras Homolog Gene Family, Member U (RHOU))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RHOU Antibody

Binding Specificity: C-Term

Purpose: RHOU Antibody - C-terminal region

Sequence: LKEVFDAAIV AGIQYSDTQQ QPKKSKSRTP DKMKNLSKSW WKKYCCFV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against RHOU. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RHOU

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110070

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHOU

Target: RHOU (Ras Homolog Gene Family, Member U (RHOU))

Alternative Name: RHOU

Background:

Background Information: RHOU is a member of the Rho family of GTPases. It can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation.This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation.

Gene Name: Ras homolog family member U

Alternative Symbols: ARHU, G28K, WRCH1, hG28K, CDC42L1

Protein Name: Rho-related GTP-binding protein RhoU

Molecular Weight: 28kDa

Gene ID: 58480

NCBI Accession: NP_067028

UniProt: Q7L0Q8