WDR5 antibody (C-Term)

Catalog No. ABIN2776738

This anti-WDR5 antibody is a Rabbit Polyclonal antibody detecting WDR5 in WB, IHC and IP. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for WDR5 antibody (C-Term) (ABIN2776738)

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-WDR5 Antibody

Binding Specificity: C-Term

Sequence: LAGHTKAVSS VKFSPNGEWL ASSSADKLIK IWGAYDGKFE KTISGHKLGI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against WDR5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 334 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WDR5

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Alternative Name: WDR5

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Alias Symbols: BIG-3, SWD3
Protein Interaction Partner: RUSC1-AS1, SSX2IP, ZXDC, MBIP, CXXC1, SETD1A, HSF2, PRMT5, NFE4, KMT2D, ING2, HDAC1, SENP3, UBC, BMI1, SRPK2, CSNK2A2, CSNK1E, KDM6B, KDM6A, NEDD8, KMT2A, BARD1, UNC45A, VPS35, CSE1L, ATP6V1B2, APP, ASH2L, USP1, TTK, PPP1CB, HCFC1, TADA3, KAT2B, TADA2A, M
Protein Size: 334

Molecular Weight: 36 kDa

Gene ID: 11091

NCBI Accession: NM_017588, NP_060058

UniProt: Q5M786