WDR5 antibody (C-Term)

Catalog No. ABIN2776739

This Rabbit Polyclonal antibody specifically detects WDR5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for WDR5 antibody (C-Term) (ABIN2776739)

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WDR5 Antibody

Binding Specificity: C-Term

Sequence: NFSVTGGKWI VSGSEDNLVY IWNLQTKEIV QKLQGHTDVV ISTACHPTEN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Wdr5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 334 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WDR5

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Alternative Name: Wdr5

Background: Wdr5 contributes to histone modification. It may position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It may regulate osteoblasts differentiation.
Alias Symbols: 2410008O07Rik, AA408785, AA960360, Big, Big-3
Protein Interaction Partner: L3mbtl2, Phf20, Rbbp5, Csrp2bp, Mbip, Kat2a, Rnf2, Pou5f1, Runx1, Ctcf, Nfe2, Kmt2d, Kdm2b, Sall4, Tfcp2l1, Esrrb, Nr0b1,
Protein Size: 334

Molecular Weight: 36 kDa

Gene ID: 140858

NCBI Accession: NM_080848, NP_543124

UniProt: P61965