PTH1R antibody (N-Term)

Catalog No. ABIN2776779

This Rabbit Polyclonal antibody specifically detects PTH1R in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Pig, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for PTH1R antibody (N-Term) (ABIN2776779)

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reactivity: Human, Rat, Mouse, Cow, Pig, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTH1R antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTH1R Antibody

Binding Specificity: N-Term

Purpose: PTH1R Antibody - N-terminal region

Sequence: ARIAPGLALL LCCPVLSSAY ALVDADDVMT KEEQIFLLHR AQAQCEKRLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTH1R. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human PTH1R

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41385-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Alternative Name: PTH1R

Background:

Background Information: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: parathyroid hormone 1 receptor

Alternative Symbols: PFE, EKNS, PTHR, PTHR1

Protein Name: parathyroid hormone/parathyroid hormone-related peptide receptor

Molecular Weight: 36kDa

Gene ID: 5745

NCBI Accession: NP_000307

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process