FOLR1 antibody (Middle Region)

Catalog No. ABIN2776804

This anti-FOLR1 antibody is a Rabbit Polyclonal antibody detecting FOLR1 in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for FOLR1 antibody (Middle Region) (ABIN2776804)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FOLR1 Antibody

Binding Specificity: Middle Region

Sequence: HFYFPTPTVL CNEIWTHSYK VSNYSRGSGR CIQMWFDPAQ GNPNEEVARF

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FOLR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOLR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 257 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FOLR1 antibody (ABIN2776804)

Azaïs, Queniat, Bonner, Kerdraon, Tardivel, Jetpisbayeva, Frochot, Betrouni, Collinet, Mordon: "Fischer 344 Rat: A Preclinical Model for Epithelial Ovarian Cancer Folate-Targeted Therapy." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 25, Issue 7, pp. 1194-200, (2015) (PubMed).

Target Details for FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: FOLR1

Background: The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anc
Alias Symbols: FBP, FOLR, FR-alpha, MOv18
Protein Interaction Partner: AGO2, NCAPH2, IRAK3, CUL3, PSMB2, IMPDH2, GSR, UBC, Poc1b, Cep76, Trim69, Dync1h1, Cdk1, Cbx1, LYN,
Protein Size: 257

Molecular Weight: 29 kDa

Gene ID: 2348

NCBI Accession: NM_000802, NP_000793

UniProt: P15328

Pathways: Dicarboxylic Acid Transport