Uromodulin antibody (Middle Region)

Catalog No. ABIN2776812

This Rabbit Polyclonal antibody specifically detects Uromodulin in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig and Rabbit.

Quick Overview for Uromodulin antibody (Middle Region) (ABIN2776812)

Target: Uromodulin (UMOD)

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uromodulin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Uromodulin Antibody

Binding Specificity: Middle Region

Purpose: UMOD Antibody - middle region

Sequence: MTNCYATPSS NATDPLKYFI IQDRCPHTRD STIQVVENGE SSQGRFSVQM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against UMOD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UMOD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41436-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Uromodulin

Target: Uromodulin (UMOD)

Alternative Name: UMOD

Background:

Background Information: This gene encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the lo

Gene Name: Uromodulin

Alternative Symbols: THP, FJHN, HNFJ, THGP, HNFJ1, MCKD2, ADTKD1, ADMCKD2

Protein Name: Uromodulin

Molecular Weight: 67kDa

Gene ID: 7369

NCBI Accession: NP_001008390

UniProt: P07911