HMGCS2 antibody (C-Term)

Catalog No. ABIN2776881

The Rabbit Polyclonal anti-HMGCS2 antibody (ABIN2776881) specifically detects HMGCS2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Goat, Horse and Cow samples.

Quick Overview for HMGCS2 antibody (C-Term) (ABIN2776881)

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Goat, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMGCS2 Antibody

Binding Specificity: C-Term

Purpose: HMGCS2 Antibody - C-terminal region

Sequence: DLPKRLASRK CVSPEEFTEI MNQREQFYHK VNFSPPGDTN SLFPGTWYLE

Predicted Reactivity: Cow: 79%, Dog: 100%, Goat: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HMGCS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HMGCS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093618

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGCS2

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Alternative Name: HMGCS2

Background:

Background Information: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.

Gene Name: 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

Alternative Symbols: -

Protein Name: Hydroxymethylglutaryl-CoA synthase, mitochondrial

Molecular Weight: 56kDa

Gene ID: 3158

NCBI Accession: NP_005509

UniProt: P54868

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha