FTCD antibody (Middle Region)

Catalog No. ABIN2776888

Cited in 1 publication. The Rabbit Polyclonal anti-FTCD antibody (ABIN2776888) specifically detects FTCD in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for FTCD antibody (Middle Region) (ABIN2776888)

Target: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTCD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FTCD Antibody

Binding Specificity: Middle Region

Purpose: FTCD Antibody - middle region

Sequence: KFLIAFNINL LGTKEQAHRI ALNLREQGRG KDQPGRLKKV QGIGWYLDEK

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FTCD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FTCD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41577-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-FTCD antibody (ABIN2776888)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Target Details for FTCD

Target: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Alternative Name: FTCD

Background:

Background Information: FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.[supplied by OMIM].

Gene Name: Formiminotransferase cyclodeaminase

Alternative Symbols: LCHC1

Protein Name: Formimidoyltransferase-cyclodeaminase

Molecular Weight: 59kDa

Gene ID: 10841

NCBI Accession: NP_006648

UniProt: O95954