Erythrocyte Ankyrin antibody (Middle Region)

Catalog No. ABIN487171

This Rabbit Polyclonal antibody specifically detects Erythrocyte Ankyrin in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for Erythrocyte Ankyrin antibody (Middle Region) (ABIN487171)

Target: Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Erythrocyte Ankyrin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Erythrocyte Ankyrin Antibody

Binding Specificity: Middle Region

Sequence: PCAMPETVVI RSEEQEQASK EYDEDSLIPS SPATETSDNI SPVASPVHTG

Predicted Reactivity: Dog: 93%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ANK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ANK1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1719 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Erythrocyte Ankyrin

Target: Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))

Alternative Name: ANK1

Background: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of spec
Alias Symbols: ANK, SPH1, SPH2
Protein Interaction Partner: UBC, SPTA1, SUMO1, CD44, TGFBR1, SPTBN1, KCTD6, OBSCN, CUL3, NEDD8, SPTB, BLOC1S6, NFASC, NBPF3, TIAM1, L1CAM, TTN, SPTAN1, RHAG, EPB42, ITPR3, SLC4A1, SLC4A3,
Protein Size: 1719

Molecular Weight: 189 kDa

Gene ID: 286

NCBI Accession: NM_020477, NP_065210

UniProt: P16157

Pathways: Synaptic Membrane