Complement C2 antibody (Middle Region)

Catalog No. ABIN2776930

The Rabbit Polyclonal anti-Complement C2 antibody has been validated for WB. It is suitable to detect Complement C2 in samples from Human, Rat, Mouse, Dog, Horse, Pig, Cow, Rabbit and Sheep.

Quick Overview for Complement C2 antibody (Middle Region) (ABIN2776930)

Target: Complement C2

Reactivity: Human, Rat, Mouse, Dog, Horse, Pig, Cow, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement C2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Complement C2 Antibody

Binding Specificity: Middle Region

Sequence: INQKRNDYLD IYAIGVGKLD VDWRELNELG SKKDGERHAF ILQDTKALHQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against C2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 752 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Complement C2

Target: Complement C2

Alternative Name: C2

Background: Component C2 is part of the classical pathway of complement system. Activated C1 cleaves C2 into C2a and C2b. C2a leads to activation of C3. Deficiency of C2 has been reported to associated with certain autoimmune diseases.Component C2 is part of the classical pathway of complement system. Activated C1 cleaves C2 into C2a and C2b. C2a leads to activation of C3. Deficiency of C2 has been reported to associated with certain autoimmune diseases.
Alias Symbols: CO2, DKFZp779M0311
Protein Interaction Partner: PSMA4, MASP1, C5, C3, C4B,
Protein Size: 752

Molecular Weight: 83 kDa

Gene ID: 717

NCBI Accession: NM_000063, NP_000054

UniProt: P06681