FANCA antibody (N-Term)

Catalog No. ABIN2776933

This Rabbit Polyclonal antibody specifically detects FANCA in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig and Pig.

Quick Overview for FANCA antibody (N-Term) (ABIN2776933)

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FANCA Antibody

Binding Specificity: N-Term

Sequence: KLSLSKVIDC DSSEAYANHS SSFIGSALQD QASRLGVPVG ILSAGMVASS

Predicted Reactivity: Cow: 83%, Dog: 92%, Guinea Pig: 79%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against FANCA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FANCA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 297 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FANCA

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Alternative Name: FANCA

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FAN
Alias Symbols: FA, FA-H, FA1, FAA, FACA, FAH, FANCH, MGC75158
Protein Interaction Partner: APITD1, STRA13, UBC, FANCG, C1orf86, FANCE, C17orf70, FANCM, FANCL, FANCB, FANCC, FANCA, BLM, TOP3A, RPA1, FANCF, MSH2, AKT1, CDK1, C19orf40, HES1, CENPE, POLN, CAPN1, BRCA1, PCNA, NPM1, ATR, SNX5, IKBKB, SMARCA4, SMARCD3, SMARCC1, SPTAN1, CHUK, RMI1, NUB
Protein Size: 297

Molecular Weight: 33 kDa

Gene ID: 2175

NCBI Accession: NM_001018112, NP_001018122

UniProt: Q86U55

Pathways: DNA Damage Repair