HMGCL antibody (N-Term)

Catalog No. ABIN2776938

This Rabbit Polyclonal antibody specifically detects HMGCL in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Guinea Pig, Cow, Zebrafish (Danio rerio) and Rabbit.

Quick Overview for HMGCL antibody (N-Term) (ABIN2776938)

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Reactivity: Human, Mouse, Rat, Dog, Horse, Guinea Pig, Cow, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMGCL Antibody

Binding Specificity: N-Term

Sequence: WVPQMGDHTE VLKGIQKFPG INYPVLTPNL KGFEAAVAAG AKEVVIFGAA

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against HMGCL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HMGCL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 325 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGCL

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Alternative Name: HMGCL

Background: The deficiency of HMGCL is related to an autosomal recessive branched chain organic aciduria.
Alias Symbols: HL
Protein Interaction Partner: GTF2B, PEX5, ADAMTS10, RNF126, ARL6IP1, DNAJA1, HES1, MS4A7,
Protein Size: 325

Molecular Weight: 36 kDa

Gene ID: 3155

NCBI Accession: NM_000191, NP_000182

UniProt: P35914