SLC2A2 antibody (N-Term)

Catalog No. ABIN2776949

There are 2+ publications for this product available. The Rabbit Polyclonal anti-SLC2A2 antibody is suitable to detect SLC2A2 in samples from Human, Rat, Mouse, Pig, Cow, Dog, Guinea Pig, Horse and Sheep. It has been validated for WB.

Quick Overview for SLC2A2 antibody (N-Term) (ABIN2776949)

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Reactivity: Human, Rat, Mouse, Pig, Cow, Dog, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC2A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC2A2 Antibody

Binding Specificity: N-Term

Sequence: ITAVLGSFQF GYDIGVINAP QQVIISHYRH VLGVPLDDRK AINNYVINST

Predicted Reactivity: Cow: 92%, Dog: 79%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against SLC2A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC2A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 524 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC2A2 antibody (ABIN2776949)

Koehler, Springer, Issel, Klinger, Strube, Breves: "Changes in porcine nutrient transport physiology in response to Ascaris suum infection." in: Parasites & vectors, Vol. 14, Issue 1, pp. 533, (2022) (PubMed).

Klinger, Lange, Brandt, Hustedt, Schröder, Breves, Herrmann: "Degree of SGLT1 phosphorylation is associated with but does not determine segment-specific glucose transport features in the porcine small intestines." in: Physiological reports, Vol. 6, Issue 1, (2018) (PubMed).

Target Details for SLC2A2

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Alternative Name: SLC2A2

Background: Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor.Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor.
Alias Symbols: GLUT2
Protein Interaction Partner: APP, PRKACA, PDX1, KPNA2, HNRNPL,
Protein Size: 524

Molecular Weight: 58 kDa

Gene ID: 6514

NCBI Accession: NM_000340, NP_000331

UniProt: P11168

Pathways: Warburg Effect