STS antibody (Middle Region)

Catalog No. ABIN2776950

This Rabbit Polyclonal antibody specifically detects STS in WB. It exhibits reactivity toward Human, Mouse, Cow, Horse, Guinea Pig, Pig, Dog, Rabbit and Zebrafish (Danio rerio).

Quick Overview for STS antibody (Middle Region) (ABIN2776950)

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Reactivity: Human, Mouse, Cow, Horse, Guinea Pig, Pig, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STS Antibody

Binding Specificity: Middle Region

Purpose: STS Antibody - middle region

Sequence: EPTSNMDIFP TVAKLAGAPL PEDRIIDGRD LMPLLEGKSQ RSDHEFLFHY

Predicted Reactivity: Cow: 90%, Dog: 80%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 77%, Pig: 92%, Rabbit: 77%, Zebrafish: 89%

Characteristics: This is a rabbit polyclonal antibody against STS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human STS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41709-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for STS

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Alternative Name: STS

Background:

Background Information: STS catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in its gene are known to cause X-linked ichthyosis The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Steroid sulfatase (microsomal), isozyme S

Alternative Symbols: ES, ASC, XLI, ARSC, SSDD, ARSC1

Protein Name: Steryl-sulfatase

Molecular Weight: 63kDa

Gene ID: 412

NCBI Accession: NP_000342

UniProt: P08842

Pathways: Steroid Hormone Biosynthesis