LOR antibody (N-Term)

Catalog No. ABIN310215

The Rabbit Polyclonal anti-LOR antibody (ABIN310215) specifically detects LOR in WB and IHC. The antibody is reactive with Human, Mouse, Cow and Guinea Pig samples.

Quick Overview for LOR antibody (N-Term) (ABIN310215)

Target: LOR (Loricrin (LOR))

Reactivity: Human, Mouse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LOR Antibody

Binding Specificity: N-Term

Purpose: LOR Antibody - N-terminal region

Sequence: GYSGGGCGGG SSGGGGGGGI GGCGGGSGGS VKYSGGGGSS GGGSGCFSSG

Predicted Reactivity: Cow: 93%, Guinea Pig: 75%, Human: 100%, Mouse: 86%

Characteristics: This is a rabbit polyclonal antibody against LOR. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LOR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104553

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LOR

Target: LOR (Loricrin (LOR))

Alternative Name: LOR

Background:

Background Information: LOR is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in LOR may be the cause of both Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.

Gene Name: Loricrin

Alternative Symbols: LOR

Protein Name: Loricrin

Molecular Weight: 26kDa

Gene ID: 4014

NCBI Accession: NP_000418

UniProt: P23490