Albumin antibody (Middle Region)

Catalog No. ABIN2776970

Product Details anti-Albumin Antibody

Target: Albumin (ALB)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Albumin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LSEKERQIKK QTALVELVKH KPKATKEQLK AVMDDFAAFV EKCCKADDKE

Predicted Reactivity: Cow: 86%, Dog: 86%, Goat: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 83%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against ALB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 609 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Albumin antibody (ABIN2776970)

Holzer, Birner-Gruenberger, Stojakovic, El-Gamal, Binder, Wadsack, Heinemann, Marsche: "Uremia alters HDL composition and function." in: Journal of the American Society of Nephrology : JASN, Vol. 22, Issue 9, pp. 1631-41, (2011) (PubMed).

Target Details for Albumin

Target: Albumin (ALB)

Alternative Name: ALB (ALB Products)

Background: Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp779N1935, PRO0883, PRO0903, PRO1341
Protein Interaction Partner: FUS, UBC, PARK2, UBD, PAN2, MYLK3, CABLES1, SLA2, TLN2, CEP44, PHC3, PALB2, QTRTD1, TTPAL, DERL1, CDCP1, TRAPPC11, SCAF1, NLRC4, IGDCC4, GJC2, CROT, EXOC6, PDZRN4, EEF2K, IGKV2-40, BBC3, LAT, SACS, SPATA31A7, AP4E1, CRB1, DICER1, OBSL1, SLC9A8, CAMTA1, SE
Protein Size: 609

Molecular Weight: 67 kDa

Gene ID: 213

NCBI Accession: NM_000477, NP_000468

UniProt: P02768

Pathways: Lipid Metabolism