Prothrombin antibody (N-Term)

Catalog No. ABIN2776975

This anti-Prothrombin antibody is a Rabbit Polyclonal antibody detecting Prothrombin in WB. Suitable for Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Sheep, Pig and Rabbit.

Quick Overview for Prothrombin antibody (N-Term) (ABIN2776975)

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Sheep, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prothrombin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Prothrombin Antibody

Binding Specificity: N-Term

Sequence: CQLWRSRYPH RPDINSTTHP GADLKENFCR NPDSSTSGPW CYTTDPTVRR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 86%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against F2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 617 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Prothrombin

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Alternative Name: F2

Background: F2 catalyzes the preferential cleavage of Arg-Gly, activates fibrinogen to fibrin and releases fibrinopeptides A and B, involved in blood coagulation and wound repair.
Alias Symbols: F2
Protein Size: 617

Molecular Weight: 70 kDa

Gene ID: 29251

NCBI Accession: NM_022924, NP_075213

UniProt: P18292

Pathways: Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling