C8G antibody (N-Term)

Catalog No. ABIN2776987

This Rabbit Polyclonal antibody specifically detects C8G in WB. It exhibits reactivity toward Human, Mouse, Dog, Horse, Pig, Rabbit, Rat, Cow and Guinea Pig.

Quick Overview for C8G antibody (N-Term) (ABIN2776987)

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Reactivity: Human, Mouse, Dog, Horse, Pig, Rabbit, Rat, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8G antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C8G Antibody

Binding Specificity: N-Term

Sequence: VGSACRFLQE QGHRAEATTL HVAPQGTAMA VSTFRKLDGI CWQVRQLYGD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against C8G. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human C8G

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C8G

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Alternative Name: C8G

Background: The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity.
Alias Symbols: C8C
Protein Interaction Partner: C8A,
Protein Size: 202

Molecular Weight: 22 kDa

Gene ID: 733

NCBI Accession: NM_000606, NP_000597

UniProt: P07360

Pathways: Complement System