C8G antibody

Catalog No. ABIN7227998

The Rabbit Polyclonal anti-C8G antibody is suitable to detect C8G in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for C8G antibody (ABIN7227998)

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8G antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-C8G Antibody

Purpose: Rabbit Anti-CO8G Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CO8G protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CO8G protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for C8G

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Alternative Name: CO8G

Background: Complement component C8 gamma chainThe Complement C8 Gamma Chain encoded by C8G belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity.

Molecular Weight: 22kD

Gene ID: 733

UniProt: P07360

Pathways: Complement System