NPY1R antibody (Middle Region)

Catalog No. ABIN2777014

Product Details anti-NPY1R Antibody

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Dog, Guinea Pig, Rabbit, Cow, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY1R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TDEPFQNVTL DAYKDKYVCF DQFPSDSHRL SYTTLLLVLQ YFGPLCFIFI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against NPY1R. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPY1R

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 384 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPY1R

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Alternative Name: NPY1R (NPY1R Products)

Synonyms: NPY1-R antibody, NPYR antibody, NPY-1 antibody, NPY1R antibody, si:dkey-253i9.3 antibody, Npyr antibody, Y1-R antibody, npy1r-A antibody, npyr antibody, neuropeptide Y receptor Y1 antibody, neuropeptide Y receptor Y1 S homeolog antibody, NPY1R antibody, Npy1r antibody, npy1r antibody, npy1r.S antibody

Background: Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle.Neuropeptide Y (NPY, MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle (Herzog et al., 1992 [PubMed 1321422]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NPYR, NPY1-R
Protein Interaction Partner: ATP13A2, LSM7, PYY, NPY,
Protein Size: 384

Molecular Weight: 44 kDa

Gene ID: 4886

NCBI Accession: NM_000909, NP_000900

UniProt: P25929

Pathways: Negative Regulation of Hormone Secretion, Feeding Behaviour