RPAIN antibody (C-Term)

Catalog No. ABIN2777047

The Rabbit Polyclonal anti-RPAIN antibody is suitable to detect RPAIN in samples from Human, Mouse, Rat, Cow, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for RPAIN antibody (C-Term) (ABIN2777047)

Target: RPAIN (RPA Interacting Protein (RPAIN))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPAIN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPAIN Antibody

Binding Specificity: C-Term

Purpose: RPAIN Antibody - C-terminal region

Sequence: VVCQCGLSIP SHSSELTEQK LRACLEGSIN EHSAHCPHTP EFSVTGGTEE

Predicted Reactivity: Cow: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against RPAIN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RPAIN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41887-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPAIN

Target: RPAIN (RPA Interacting Protein (RPAIN))

Alternative Name: RPAIN

Background:

Background Information: RPAIN mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism.

Gene Name: RPA interacting protein

Alternative Symbols: RIP, HRIP

Protein Name: RPA-interacting protein

Molecular Weight: 25kDa

Gene ID: 84268

NCBI Accession: NP_001028174

UniProt: Q86UA6

Pathways: Protein targeting to Nucleus