SIGLEC6 antibody (N-Term)

Catalog No. ABIN2777066

This Rabbit Polyclonal antibody specifically detects SIGLEC6 in WB. It exhibits reactivity toward Human, Cow, Horse and Pig.

Quick Overview for SIGLEC6 antibody (N-Term) (ABIN2777066)

Target: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Reactivity: Human, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGLEC6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIGLEC6 Antibody

Binding Specificity: N-Term

Purpose: SIGLEC6 Antibody - N-terminal region

Sequence: VPVATNDPDE EVQEETRGRF HLLWDPRRKN CSLSIRDARR RDNAAYFFRL

Predicted Reactivity: Cow: 79%, Horse: 86%, Human: 100%, Pig: 100%

Characteristics: This is a rabbit polyclonal antibody against SIGLEC6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SIGLEC6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41925-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIGLEC6

Target: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Alternative Name: SIGLEC6

Background:

Background Information: SIGLEC6 is a Putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Gene Name: Sialic acid binding Ig-like lectin 6

Alternative Symbols: CD327, CD33L, OBBP1, CD33L1, CD33L2, CDW327

Protein Name: Sialic acid-binding Ig-like lectin 6

Molecular Weight: 47kDa

Gene ID: 946

NCBI Accession: NP_001236

UniProt: O43699