Glutathione Peroxidase 2 antibody (Middle Region)

Catalog No. ABIN2777110

The Rabbit Polyclonal anti-Glutathione Peroxidase 2 antibody is suitable to detect Glutathione Peroxidase 2 in samples from Human, Mouse, Rat, Dog, Pig, Cow and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Glutathione Peroxidase 2 antibody (Middle Region) (ABIN2777110)

Target: Glutathione Peroxidase 2 (GPX2)

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Peroxidase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutathione Peroxidase 2 Antibody

Binding Specificity: Middle Region

Purpose: GPX2 Antibody - middle region

Sequence: GGGYQPTFTL VQKCEVNGQN EHPVFAYLKD KLPYPYDDPF SLMTDPKLII

Predicted Reactivity: Cow: 100%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against GPX2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GPX2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42018-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glutathione Peroxidase 2

Target: Glutathione Peroxidase 2 (GPX2)

Alternative Name: GPX2

Background:

Background Information: This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.

Gene Name: Glutathione peroxidase 2 (gastrointestinal)

Alternative Symbols: GPRP, GPx-2, GI-GPx, GPRP-2, GPx-GI, GSHPx-2, GSHPX-GI

Protein Name: Glutathione peroxidase 2

Molecular Weight: 22kDa

Gene ID: 2877

NCBI Accession: NP_002074

UniProt: P18283

Pathways: Thyroid Hormone Synthesis