PF4V1 antibody (Middle Region)

Catalog No. ABIN2777124

Cited in 1 publication. The Rabbit Polyclonal anti-PF4V1 antibody (ABIN2777124) specifically detects PF4V1 in WB. The antibody is reactive with Human and Pig samples.

Quick Overview for PF4V1 antibody (Middle Region) (ABIN2777124)

Target: PF4V1 (Platelet Factor 4 Variant 1 (PF4V1))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PF4V1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PF4V1 Antibody

Binding Specificity: Middle Region

Purpose: PF4V1 Antibody - middle region

Sequence: RPRHITSLEV IKAGPHCPTA QLIATLKNGR KICLDLQALL YKKIIKEHLE

Predicted Reactivity: Human: 100%, Pig: 85%

Characteristics: This is a rabbit polyclonal antibody against PF4V1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PF4V1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42053-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-PF4V1 antibody (ABIN2777124)

Struyf, Burdick, Proost, Van Damme, Strieter: "Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis." in: Circulation research, Vol. 95, Issue 9, pp. 855-7, (2004) (PubMed).

Target Details for PF4V1

Target: PF4V1 (Platelet Factor 4 Variant 1 (PF4V1))

Alternative Name: PF4V1

Background:

Background Information: PF4V1 is the inhibitor of angiogenesis. PF4V1 is the inhibitor of endothelial cell chemotaxis (in vitro).

Gene Name: Platelet factor 4 variant 1

Alternative Symbols: PF4A, CXCL4L1, CXCL4V1, PF4-ALT, SCYB4V1

Protein Name: Platelet factor 4 variant

Molecular Weight: 11kDa

Gene ID: 5197

NCBI Accession: NP_002611

UniProt: P10720