SEMG1 antibody (N-Term)

Catalog No. ABIN2777136

The Rabbit Polyclonal anti-SEMG1 antibody (ABIN2777136) specifically detects SEMG1 in WB and IHC. The antibody is reactive with Human and Pig samples.

Quick Overview for SEMG1 antibody (N-Term) (ABIN2777136)

Target: SEMG1 (Semenogelin I (SEMG1))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SEMG1 Antibody

Binding Specificity: N-Term

Purpose: SEMG1 Antibody - N-terminal region

Sequence: QKGKQQTESK GSFSIQYTYH VDANDHDQSR KSQQYDLNAL HKTTKSQRHL

Predicted Reactivity: Human: 100%, Pig: 86%

Characteristics: This is a rabbit polyclonal antibody against SEMG1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SEMG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42088-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEMG1

Target: SEMG1 (Semenogelin I (SEMG1))

Alternative Name: SEMG1

Background:

Background Information: SEMG1 is the predominant protein in semen. The secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely.The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Semenogelin I

Alternative Symbols: SGI, SEMG, CT103, dJ172H20.2

Protein Name: Semenogelin-1

Molecular Weight: 51kDa

Gene ID: 6406

NCBI Accession: NP_002998

UniProt: P04279