SEMG1 antibody (C-Term)

Catalog No. ABIN2777138

This Rabbit Polyclonal antibody specifically detects SEMG1 in WB. It exhibits reactivity toward Human and Pig.

Quick Overview for SEMG1 antibody (C-Term) (ABIN2777138)

Target: SEMG1 (Semenogelin I (SEMG1))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SEMG1 Antibody

Binding Specificity: C-Term

Sequence: GENGVQKDVS QSSIYSQTEE KAQGKSQKQI TIPSQEQEHS QKANKISYQS

Predicted Reactivity: Human: 100%, Pig: 77%

Characteristics: This is a rabbit polyclonal antibody against SEMG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SEMG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 462 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEMG1

Target: SEMG1 (Semenogelin I (SEMG1))

Alternative Name: SEMG1

Background: SEMG1 is the predominant protein in semen. The secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely.The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC14719, SEMG, SGI, CT103, dJ172H20.2
Protein Interaction Partner: FBXW4, SUMO2, PIK3R2, UBQLN4, CDK2, UBC, TGM1, SEMG2, PRKCA, KLK3, KLK2,
Protein Size: 462

Molecular Weight: 51 kDa

Gene ID: 6406

NCBI Accession: NM_003007, NP_002998

UniProt: P04279