Stanniocalcin 1 antibody (N-Term)

Catalog No. ABIN2777144

This Rabbit Polyclonal antibody specifically detects Stanniocalcin 1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Dog, Pig, Cow, Guinea Pig and Rabbit.It has been mentioned in 1 publication

Quick Overview for Stanniocalcin 1 antibody (N-Term) (ABIN2777144)

Target: Stanniocalcin 1 (STC1)

Reactivity: Human, Mouse, Rat, Horse, Dog, Pig, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stanniocalcin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Stanniocalcin 1 Antibody

Binding Specificity: N-Term

Purpose: STC1 Antibody - N-terminal region

Sequence: MLQNSAVLLV LVISASATHE AEQNDSVSPR KSRVAAQNSA EVVRCLNSAL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against STC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42104-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Stanniocalcin 1 antibody (ABIN2777144)

Gao, Xu, Chen, Wang, Wang, Wu, Yuan: "Potential protein toxicity of synthetic pigments: binding of poncean S to human serum albumin." in: Biophysical journal, Vol. 94, Issue 3, pp. 906-17, (2008) (PubMed).

Target Details for Stanniocalcin 1

Target: Stanniocalcin 1 (STC1)

Alternative Name: STC1

Background:

Background Information: STC1 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. It contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate.This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Stanniocalcin 1

Alternative Symbols: STC

Protein Name: Stanniocalcin-1

Molecular Weight: 28 kDa

Gene ID: 6781

NCBI Accession: NP_003146

UniProt: P52823

Pathways: Hormone Activity