LEFTY2 antibody (N-Term)

Catalog No. ABIN2777147

The Rabbit Polyclonal anti-LEFTY2 antibody is suitable to detect LEFTY2 in samples from Human, Rat, Pig and Dog. It has been validated for WB.

Quick Overview for LEFTY2 antibody (N-Term) (ABIN2777147)

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Reactivity: Human, Rat, Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEFTY2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LEFTY2 Antibody

Binding Specificity: N-Term

Purpose: LEFTY2 Antibody - N-terminal region

Sequence: AGPGAALTEE QLLGSLLRQL QLSEVPVLDR ADMEKLVIPA HVRAQYVVLL

Predicted Reactivity: Dog: 83%, Human: 100%, Pig: 77%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against LEFTY2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LEFTY2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42108-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LEFTY2

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Alternative Name: LEFTY2

Background:

Background Information: LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.

Gene Name: left-right determination factor 2

Alternative Symbols: EBAF, LEFTA, TGFB4, LEFTYA

Protein Name: Left-right determination factor 2

Molecular Weight: 40kDa

Gene ID: 7044

NCBI Accession: NP_003231

UniProt: O00292