RDH16 antibody (N-Term)

Catalog No. ABIN2777160

This Rabbit Polyclonal antibody specifically detects RDH16 in WB. It exhibits reactivity toward Human, Dog, Horse, Cow, Mouse, Guinea Pig, Pig and Rat.

Quick Overview for RDH16 antibody (N-Term) (ABIN2777160)

Target: RDH16 (Retinol Dehydrogenase 16 (All-Trans) (RDH16))

Reactivity: Human, Dog, Horse, Cow, Mouse, Guinea Pig, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDH16 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RDH16 Antibody

Binding Specificity: N-Term

Purpose: RDH16 Antibody - N-terminal region

Sequence: WLYLAVFVGL YYLLHWYRER QVLSHLRDKY VFITGCDSGF GKLLARQLDA

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against RDH16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RDH16

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42141-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RDH16

Target: RDH16 (Retinol Dehydrogenase 16 (All-Trans) (RDH16))

Alternative Name: RDH16

Background:

Background Information: RDH16 is an oxidoreductase with a preference for NAD. It oxidizes all-trans-retinol and 13-cis-retinol to the corresponding aldehydes. RDH16 has higher activity towards CRBP-bound retinol than with free retinol. It also oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. RDH16 can also catalyze the reverse reaction.

Gene Name: Retinol dehydrogenase 16 (all-trans)

Alternative Symbols: RODH-4, SDR9C8, hRDH-E

Protein Name: Retinol dehydrogenase 16

Molecular Weight: 36kDa

Gene ID: 8608

NCBI Accession: NP_003699

UniProt: O75452

Pathways: Steroid Hormone Biosynthesis