Leukotriene B4 Receptor/BLT antibody (C-Term)
Quick Overview for Leukotriene B4 Receptor/BLT antibody (C-Term) (ABIN567075)
Target
See all Leukotriene B4 Receptor/BLT (LTB4R) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- AGQAAGLGLV GKRLSLARNV LIALAFLSSS VNPVLYACAG GGLLRSAGVG
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Predicted Reactivity
- Human: 100%
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Characteristics
- This is a rabbit polyclonal antibody against LTB4R. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human LTB4R
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 352 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))
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Alternative Name
- LTB4R
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Background
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LTB4R is the receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. LTB4R may be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. LTB4R is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Alias Symbols: BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7
Protein Interaction Partner: GNAI2, LTB4R, YWHAG, GRK6, GNA15,
Protein Size: 352 -
Molecular Weight
- 37 kDa
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Gene ID
- 1241
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NCBI Accession
- NM_181657, NP_858043
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UniProt
- Q15722
Target
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