HOXD4 antibody (C-Term)

Catalog No. ABIN2777273

The Rabbit Polyclonal anti-HOXD4 antibody (ABIN2777273) specifically detects HOXD4 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Pig and Horse samples.

Quick Overview for HOXD4 antibody (C-Term) (ABIN2777273)

Target: HOXD4 (Homeobox D4 (HOXD4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOXD4 Antibody

Binding Specificity: C-Term

Purpose: HOXD4 Antibody - C-terminal region

Sequence: RMKWKKDHKL PNTKGRSSSS SSSSSCSSSV APSQHLQPMA KDHHTDLTTL

Predicted Reactivity: Cow: 93%, Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HOXD4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31391-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXD4

Target: HOXD4 (Homeobox D4 (HOXD4))

Alternative Name: HOXD4

Background:

Background Information: HOXD4 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.

Gene Name: Homeobox D4

Alternative Symbols: HOX4, HOX4B, HHO.C13, HOX-5.1, Hox-4.2

Protein Name: Homeobox protein Hox-D4

Molecular Weight: 28kDa

Gene ID: 3233

NCBI Accession: NP_055436

UniProt: P09016