IKZF1 antibody (Middle Region)

Catalog No. ABIN2777317

The Rabbit Polyclonal anti-IKZF1 antibody (ABIN2777317) specifically detects IKZF1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig and Rabbit samples.

Quick Overview for IKZF1 antibody (Middle Region) (ABIN2777317)

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IKZF1 Antibody

Binding Specificity: Middle Region

Purpose: IKZF1 Antibody - middle region

Sequence: DLCKIGSERS LVLDRLASNV AKRKSSMPQK FLGDKGLSDT PYDSSASYEK

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against IKZF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IKZF1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31470-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IKZF1

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Alternative Name: IKZF1

Background:

Background Information: IKZF1 binds and activates the enhancer (delta-A element) of the CD3-delta gene. It functions in the specification and the maturation of the T-lymphocyte. It also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development.

Gene Name: IKAROS family zinc finger 1 (Ikaros)

Alternative Symbols: IK1, LYF1, LyF-1, CVID13, IKAROS, PPP1R92, PRO0758, ZNFN1A1, Hs.54452

Protein Name: DNA-binding protein Ikaros

Molecular Weight: 57kDa

Gene ID: 10320

NCBI Accession: NP_006051

UniProt: Q13422

Pathways: Production of Molecular Mediator of Immune Response