HMG20A antibody (N-Term)

Catalog No. ABIN2777318

This Rabbit Polyclonal antibody specifically detects HMG20A in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Horse, Cow and Guinea Pig.

Quick Overview for HMG20A antibody (N-Term) (ABIN2777318)

Target: HMG20A (High-Mobility Group 20A (HMG20A))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMG20A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMG20A Antibody

Binding Specificity: N-Term

Purpose: HMG20A Antibody - N-terminal region

Sequence: MENLMTSSTL PPLFADEDGS KESNDLATTG LNHPEVPYSS GATSSTNNPE

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 82%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HMG20A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HMG20A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31471-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMG20A

Target: HMG20A (High-Mobility Group 20A (HMG20A))

Alternative Name: HMG20A

Background:

Background Information: HMG20A plays a role in neuronal differentiation as chromatin-associated protein. It overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. The protein also act as inhibitor of HMG20B. It involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4.

Gene Name: High mobility group 20A

Alternative Symbols: HMGX1, HMGXB1

Protein Name: High mobility group protein 20A

Molecular Weight: 40kDa

Gene ID: 10363

NCBI Accession: NP_060670

UniProt: Q9NP66