Advillin antibody (N-Term)

Catalog No. ABIN2777326

The Rabbit Polyclonal anti-Advillin antibody (ABIN2777326) specifically detects Advillin in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for Advillin antibody (N-Term) (ABIN2777326)

Target: Advillin (AVIL)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Advillin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Advillin Antibody

Binding Specificity: N-Term

Purpose: Avil Antibody - N-terminal region

Sequence: SGERLXXXXX XKAMLLAKDI RDREGGGRAE IGVIEGDKEA ASPELMTVLQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 93%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Avil. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31494-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Advillin

Target: Advillin (AVIL)

Alternative Name: Avil

Background:

Background Information: Avil is a Ca2+-regulated actin-binding protein. It may have a unique function in the morphogenesis of neuronal cells which form ganglia. It is required for SREC1-mediated regulation of neurite-like outgrowth. It plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. It is involved in the formation of long fine actin-containing filopodia-like structures in fibroblast and is required for SREC1-mediated regulation of neurite-like outgrowth. Avil plays a role in ciliogenesis.

Gene Name: Advillin

Alternative Symbols: -

Protein Name: Advillin

Molecular Weight: 91kDa

Gene ID: 79253

NCBI Accession: NP_077377

UniProt: Q9WU06

Pathways: Regulation of Actin Filament Polymerization