ZNF384 antibody (Middle Region)

Catalog No. ABIN2777372

The Rabbit Polyclonal anti-ZNF384 antibody (ABIN2777372) specifically detects ZNF384 in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for ZNF384 antibody (Middle Region) (ABIN2777372)

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF384 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZNF384 Antibody

Binding Specificity: Middle Region

Purpose: ZNF384 Antibody - middle region

Sequence: KKKRMLESGL PEMNDPYVLS PEDDDDHQKD GKTYRCRMCS LTFYSKSEMQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ZNF384. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZNF384

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31601-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF384

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Alternative Name: ZNF384

Background:

Background Information: The specific function of this protein remains unknownThis gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene.

Gene Name: Zinc finger protein 384

Alternative Symbols: NP, CIZ, NMP4, CAGH1, ERDA2, TNRC1, CAGH1A

Molecular Weight: 54kDa

Gene ID: 171017

NCBI Accession: NP_001035008

UniProt: A8MQD1