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SCMH1 antibody (Middle Region)

SCMH1 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777417
  • Target See all SCMH1 Antibodies
    SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))
    Binding Specificity
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Saccharomyces cerevisiae
    Host
    • 17
    • 6
    Rabbit
    Clonality
    • 19
    • 4
    Polyclonal
    Conjugate
    • 19
    • 2
    • 1
    • 1
    This SCMH1 antibody is un-conjugated
    Application
    • 17
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LTGDNLQPPG TKVVIPKNPY PASDVNTEKP SIHSSTKTVL EHQPGQRGRK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 86%, Yeast: 79%
    Characteristics
    This is a rabbit polyclonal antibody against SCMH1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SCMH1
    Top Product
    Discover our top product SCMH1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 591 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))
    Alternative Name
    SCMH1 (SCMH1 Products)
    Synonyms
    Scml3 antibody, AI315320 antibody, AI851618 antibody, Scml1 antibody, zgc:162582 antibody, Scm polycomb group protein homolog 1 antibody, sex comb on midleg homolog 1 (Drosophila) antibody, sex comb on midleg homolog 1 antibody, Scm polycomb group protein homolog 1 L homeolog antibody, SCMH1 antibody, Scmh1 antibody, scmh1 antibody, scmh1.L antibody
    Background
    SCMH1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
    Alias Symbols: Scml3
    Protein Interaction Partner: UBQLN1, RNF2, MAGEA12, BMI1, UBQLN4, PHC3, CBX4, PCGF2, PHC2, PHC1, MAML3, LZTR1, PCBD1, EWSR1, TMEM11, SCMH1, MOB4, TOB1, POLR2M, LYPLA2, GMNN, HK1, Cbx2,
    Protein Size: 591
    Molecular Weight
    65 kDa
    Gene ID
    22955
    NCBI Accession
    NM_012236, NP_036368
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