SOX1 antibody (Middle Region)

Catalog No. ABIN2777427

This Rabbit Polyclonal antibody specifically detects SOX1 in WB. It exhibits reactivity toward Human, Mouse, Rabbit, Cow, Dog and Zebrafish (Danio rerio).

Quick Overview for SOX1 antibody (Middle Region) (ABIN2777427)

Target: SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))

Reactivity: Human, Mouse, Rabbit, Cow, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOX1 Antibody

Binding Specificity: Middle Region

Purpose: SOX1 Antibody - middle region

Sequence: AAGGAHQNSA VAAAAAAAAA SSGALGALGS LVKSEPSGSP PAPAHSRAPC

Predicted Reactivity: Cow: 93%, Dog: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 80%

Characteristics: This is a rabbit polyclonal antibody against SOX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112795

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOX1

Target: SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))

Alternative Name: SOX1

Background:

Background Information: SOX1 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX1 may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.

Gene Name: SRY (sex determining region Y)-box 1

Alternative Symbols: -

Protein Name: Transcription factor SOX-1

Molecular Weight: 39kDa

Gene ID: 6656

NCBI Accession: NP_005977

UniProt: O00570