TLR6 antibody (Middle Region)

Catalog No. ABIN2777430

Product Details anti-TLR6 Antibody

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Binding Specificity: Middle Region

Reactivity: Human, Goat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KCLVRVFQFL WPKPVEYLNI YNLTIIESIR EEDFTYSKTT LKALTIEHIT

Predicted Reactivity: Goat: 85%, Human: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against TLR6. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TLR6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 480 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLR6

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Alternative Name: TLR6 (TLR6 Products)

Background: TLR6 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins.
Alias Symbols: CD286
Protein Interaction Partner: BTK, TRAP1, TLR2,
Protein Size: 480

Molecular Weight: 53 kDa

Gene ID: 10333

NCBI Accession: NM_006068

UniProt: Q2NKL3

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades