Activator of Basal Transcription 1 antibody (N-Term)

Catalog No. ABIN2777494

This Rabbit Polyclonal antibody specifically detects Activator of Basal Transcription 1 in WB. It exhibits reactivity toward Human, Cow, Dog and Rabbit.

Quick Overview for Activator of Basal Transcription 1 antibody (N-Term) (ABIN2777494)

Target: Activator of Basal Transcription 1 (Abt1)

Reactivity: Human, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Activator of Basal Transcription 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Activator of Basal Transcription 1 Antibody

Binding Specificity: N-Term

Purpose: ABT1 Antibody - N-terminal region

Sequence: VGRVFFQAED RFVRRKKKAA AAAGGKKRSY TKDYTEGWVE FRDKRIAKRV

Predicted Reactivity: Cow: 86%, Dog: 79%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against ABT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ABT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31915-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Activator of Basal Transcription 1

Target: Activator of Basal Transcription 1 (Abt1)

Alternative Name: ABT1

Background:

Background Information: Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by ABT1 likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.

Gene Name: Activator of basal transcription 1

Alternative Symbols: Esf2, hABT1

Protein Name: Activator of basal transcription 1

Molecular Weight: 32kDa

Gene ID: 29777

NCBI Accession: NP_037507

UniProt: Q9ULW3