MAP4K6 antibody (Middle Region)
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- Target See all MAP4K6 (MINK1) Antibodies
- MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Pig, Cow, Horse, Dog, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAP4K6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PDSSPVLSPG NKAKPDDHRS RPGRPADFVL LKERTLDEAP RPPKKAMDYS
- Predicted Reactivity
- Cow: 85%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MINK1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MINK1
- Top Product
- Discover our top product MINK1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1312 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))
- Alternative Name
- MINK1 (MINK1 Products)
- Background
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MINK1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways.This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
Alias Symbols: B55, MAP4K6, MGC21111, MINK, YSK2, ZC3, hMINK, hMINKbeta
Protein Interaction Partner: UBC, HSP90AA1, NEDD4L, CASKIN1, SPTBN2, PKP4, ABI1, TUBA1B, KIFAP3, YWHAB, YWHAZ, NCK1, NEFM, MAP1B, CALM3, ACTA2,
Protein Size: 1312 - Molecular Weight
- 148 kDa
- Gene ID
- 50488
- NCBI Accession
- NM_001024937, NP_001020108
- UniProt
- Q5U8Z0
- Pathways
- Synaptic Membrane
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