KLF2 antibody (Middle Region)

Catalog No. ABIN2777573

There is 1 publication for this product available. The Rabbit Polyclonal anti-KLF2 antibody is suitable to detect KLF2 in samples from Human, Mouse, Rat, Pig, Zebrafish (Danio rerio) and Guinea Pig. It has been validated for WB, IHC and ChIP.

Quick Overview for KLF2 antibody (Middle Region) (ABIN2777573)

Target: KLF2 (Kruppel-Like Factor 2 (Lung) (KLF2))

Reactivity: Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Product Details anti-KLF2 Antibody

Binding Specificity: Middle Region

Purpose: KLF2 Antibody - middle region

Sequence: PPAFGLFDDA AAAAAALGLA PPAARGLLTP PASPLELLEA KPKRGRRSWP

Predicted Reactivity: Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against KLF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KLF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32760-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-KLF2 antibody (ABIN2777573)

Yamada, Park, Mamonkin, Lacorazza: "Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2." in: Nature immunology, Vol. 10, Issue 6, pp. 618-26, (2009) (PubMed).

Target Details for KLF2

Target: KLF2 (Kruppel-Like Factor 2 (Lung) (KLF2))

Alternative Name: KLF2

Background:

Background Information: KLF2 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription.

Gene Name: Kruppel-like factor 2 (lung)

Alternative Symbols: LKLF

Protein Name: Krueppel-like factor 2

Molecular Weight: 37kDa

Gene ID: 10365

NCBI Accession: NP_057354

UniProt: Q9Y5W3